Disprot - Database of Protein Disorder

Annotation for this protein is in progress - please check future releases for more complete information

DP00195: Non-histone chromosomal protein HMG-17

General information
DisProt:	DP00195
Name:	Non-histone chromosomal protein HMG-17
Synonym(s):	HMGN2_BOVIN High-mobility group nucleosome-binding domain-containing protein 2 HMG-17
First appeared in release:	Release 2.0 (02/14/2005)
UniProt:	P02313
UniGene:	Bt.1758
SwissProt:	HMGN2_BOVIN
TrEMBL:
NCBI (GI):	189047100
Source organism:	Bos taurus (Bovine)
Sequence length:	89
Percent disordered:	100%
Homologues:

Native sequence

10 20 30 40 50 60
| | | | | |
PKRKAEGDAK GDKAKVKDEP QRRSARLSAK PAPPKPEPKP KKAPAKKGEK VPKGKKGKAD - 60
AGKBGBBPAZ BGBAKTBZAZ KAEGAGDAK

Map of ordered and disordered regions
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.

Region 1
Type:	Disordered
Name:
Location:	1 - 89
Length:	89
Region sequence:	PKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKAD AGKBGBBPAZBGBAKTBZAZKAEGAGDAK
Modification type:	Monomeric Mutant
PDB:
Structural/functional type:	Function arises via a disorder to order transition
Functional classes:	Molecular assembly
Functional subclasses:	Protein-DNA binding
Detection methods: Fourier transform infrared spectroscopy (FTIR), aka infrared spectroscopy) (pH: 6.8; NaCl 1 M) Small-angle neutron scattering (SANS) (pH: 7; Phosphate buffer 50 mM) Circular dichroism (CD) spectroscopy, far-UV (pH: 7.9; NaCl 1 M; Tris-HCl (buffer) 20 mM)
References: Abercrombie BD, Kneale GG, Crane-Robinson C, Bradbury EM, Goodwin GH, Walker JM, Johns EW. "Studies on the conformational properties of the high-mobility-group chromosomal protein HMG 17 and its interaction with DNA." Eur J Biochem. 1978; 84(1): 173-7. PubMed: 565710
Comments: