| General information | | DisProt: | DP00667 | | Name: | Dehydrin ERD14 | | Synonym(s): | ERD14_ARATH
| | First appeared in release: | Release 5.1 (05/28/2010) | | UniProt: | P42763 | | UniGene: | At.47606 | | SwissProt: | ERD14_ARATH | | TrEMBL: | | | NCBI (GI): | 1169278 | | Source organism: | Arabidopsis thaliana (Mouse-ear cress) | | Sequence length: | 185 | | Percent disordered: | 100% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
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MAEEIKNVPE QEVPKVATEE SSAEVTDRGL FDFLGKKKDE TKPEETPIAS EFEQKVHISE - 60
PEPEVKHESL LEKLHRSDSS SSSSSEEEGS DGEKRKKKKE KKKPTTEVEV KEEEKKGFME - 120
KLKEKLPGHK KPEDGSAVAA APVVVPPPVE EAHPVEKKGI LEKIKEKLPG YHPKTTVEEE - 180
KKDKE
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| Functional narrative |
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity.
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| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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| Region 1 | | Type: | Disordered | | Name: | | | Location: | 1 - 185 | | Length: | 185 | | Region sequence: |
MAEEIKNVPEQEVPKVATEESSAEVTDRGLFDFLGKKKDETKPEETPIASEFEQKVHISE
PEPEVKHESLLEKLHRSDSSSSSSSEEEGSDGEKRKKKKEKKKPTTEVEVKEEEKKGFME
KLKEKLPGHKKPEDGSAVAAAPVVVPPPVEEAHPVEKKGILEKIKEKLPGYHPKTTVEEE
KKDKE | | Modification type: | Native
| | PDB: | | | Structural/functional type: | | | Functional classes: | Chaperones
| | Functional subclasses: | | Detection methods:
- SDS-PAGE gel, Aberrant mobility on (373 K; BSA (control) 0.2 mg/mL; SDS-PAGE Gel (12.5%); ERD14 (sample) 0.3 mg/mL)
- Circular dichroism (CD) spectroscopy, far-UV (298 K; pH: 7.5; ERD14 (sample) 0.5 mg/mL; NaCl 100 mM; phosphate buffer (NaH2PO4) 10 mM)
- Nuclear magnetic resonance (NMR) (298 K; ERD14 (sample) 1 mM; H2O:D2O (9:1, v/v))
| References:
- Kovacs D, Kalmar E, Torok Z, Tompa P. "Chaperone Activity of ERD10 and ERD14, Two Disordered Stress-Related Plant Proteins." Plant Physiol. : 381-390. PubMed: 18359842
| Comments:
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| Comments |
Additional UniGene ID: At.73066, At.73994
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